Due to the large amount of malware-related problems associated with Microsoft AutoRun,panda have created a free utility called Panda USB Vaccine to protect your USB Drive from Autorun Virus.
panda USB Vaccine is a light weight and portable PC utility, that protects and prevents viruses spreading through your USB devices.
Now days,almost every one is using a USB drive for data storage and transfers.Many viruses then take advantage of the Autorun.inf fileto spread by infecting as soon as a new drive is inserted in a computer.
Panda USB Vaccine effectivelly disables Windows from automatically executing any malicious file that might be stored in that particular USB drive. The drive can otherwise be used normally and files (even malware) copied to/from it, but they will be prevented from opening automatically. Panda USB Vaccine currently only works on FAT & FAT32 USB drives. Also keep in mind that USB drives that have been vaccinated cannot be reversed except with a format.